REM sleep without atonia and the relation with Lewy body disease
نویسندگان
چکیده
منابع مشابه
REM sleep without atonia in middle-aged and older psychiatric patients and Lewy body disease: a case series.
OBJECTIVE Rapid eye movement (REM) sleep behavior disorder (RBD) is commonly associated with Lewy body disease, narcolepsy, or depression. In contrast, the relationship between REM sleep without atonia (RWA), which is a hallmark of RBD on polysomnography, and clinical characteristics remains unclear. The purpose of this study is to investigate the clinical features of psychiatric patients exhib...
متن کاملREM sleep behavior disorder and REM sleep without atonia in patients with progressive supranuclear palsy.
STUDY OBJECTIVE To compare sleep characteristics, rapid eye movement (REM) sleep without atonia, and REM sleep behavior disorder (RBD) in patients with progressive supranuclear palsy (tauopathy), patients with Parkinson's disease (a synucleinopathy), and control subjects. DESIGN Sleep interview, overnight polysomnography, and Multiple Sleep Latency Tests. PATIENTS Forty-five age- and sex-ma...
متن کاملREM sleep without atonia after lesions of the medial medulla.
Rapid eye movement (REM) sleep is normally accompanied by a complete suppression of tone in the antigravity musculature. Pontine lesions have been shown to block this suppression, producing a syndrome of REM sleep without atonia. We now report that glutamate-induced lesions of the medial medulla, including the nucleus magnocellularis, caudal nucleus gigantocellularis and rostral nucleus paramed...
متن کاملCHOLINERGIC STIMULATION of the rostral part of the pontine reticular formation induces rapid-eye-movement (REM) sleep with atonia in intact animals, and lesions at this pontine site cause REM sleep without atonia.1,2,3 REM sleep without atonia
pontine reticular formation induces rapid-eye-movement (REM) sleep with atonia in intact animals, and lesions at this pontine site cause REM sleep without atonia.1,2,3 REM sleep without atonia is also induced by lesions in the medial medulla.4,5 In the decerebrate cat, both chemical and electrical stimulation delivered to the pontine inhibitory regions, as well as to portions of the medial medu...
متن کاملLesions producing REM sleep without atonia disinhibit the acoustic startle reflex without affecting prepulse inhibition.
This study determined whether the brainstem motor inhibition system that mediates muscle atonia during rapid eye movement (REM) sleep is involved in the elicitation and prepulse inhibition of the acoustic startle reflex. Electrolytic or neurotoxic (glutamate) lesions were made in the dorsolateral pontine tegmentum or the medial medulla, respectively, to produce the syndrome of REM sleep without...
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ژورنال
عنوان ژورنال: Parkinsonism & Related Disorders
سال: 2019
ISSN: 1353-8020
DOI: 10.1016/j.parkreldis.2019.07.007